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Encephalopathy was associated with an increase in mortality when graded by the Glasgow Coma Score;a score of 15 had 16%mortality,13 to 14 had 20%,9 to 12 had 50%,and 3 to 8 had 63%mortality(P<.05).Bacteria was associated with encephalopathy;13%of septic patients without encephalopathy vs 59%of patients with encephalopathy had bacteria(P<.001)when graded by altered mental status.Septic encephalopathy patients had elevated serum urea nitrogen and bilirubin levels,increased APACHE II scores,and a higher incidence of renal failure.The severity of septic encephalopathy correlated with mortality,bacteremia,and renal and hepatic dysfunction.The Glasgow Coma Score is a useful tool for characterizing septic encephalopathy.Considerable variations can be found to different criteria used to classify septic encephalopathy. |
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